嗜碱性粒细胞(basophil)和嗜酸性粒细胞(eosinophil)的区别

让我们先简单地看一下血液的成分，以便清楚地了解嗜碱性粒细胞和嗜酸性粒细胞的区别。血液主要由白细胞、红细胞、血小板和血浆组成。血浆是血液的液体部分，占血液体积的一半以上。白细胞约占整个血容量的1%，红细胞约占45%。白细胞或白细胞分为有颗粒或无颗粒的细胞。颗粒白细胞包括中性粒细胞、嗜酸性粒细胞和嗜碱性粒细胞，非颗粒白细胞包括淋巴细胞和单核细胞。嗜碱性粒细胞和嗜酸性粒细胞之间的关键区别在于嗜碱性粒细胞可以通过释放肝素、组胺和血清素来**炎症反应，而嗜酸性粒细胞则通过吞噬作用和产生抗组胺药来对抗寄生虫。

什么是嗜碱性粒细胞(basophil)？

Basophils are granular leukocytes with an S-shaped multi-lobed nucleus and are similar to the size of eosinophils. These cells stimulate inflammation resp***es by releasing heparin, histamine, and serotonin. Biologists believe that basophils are produced and matured in the bone marrow. Certain morphological and functional features of basophils are equal to mast cells, which are common in tissues. Basophils are hardly seen in the blood of healthy humans, because once they release, they circulate for a few hours in the blood and migrate to the tissues where they last a few days. Basophils have relatively few granules, which are water soluble. Therefore, identifying basophils in blood is quite difficult. However, when basic stains are used to identify, the cytopla** of the basophils stain blue in color.

什么是嗜酸性粒细胞(eosinophil)？

Eosinophils are bone marrow derived granular leukocytes with two-lobed nucleus. They provide an important defense against parasites by phagocytosis and produce antihistamines.  When acid stains are used, the cytopla** of the eosinophil stains in red. Usually, 1% to 5% of white blood cells are eosinophils. Very low number of eosinophils are found in the blood circulation of healthy pers*** because these cells are primarily tissue-dwelling cells.

嗜碱性粒细胞(basophil)和嗜酸性粒细胞(eosinophil)的区别

嗜碱性粒细胞和嗜酸性粒细胞的特征

细胞核

嗜碱性粒细胞：嗜碱性粒细胞有S形多裂核。

嗜酸性粒细胞：嗜酸性粒细胞有两个裂核。

染色颜色

嗜碱性粒细胞：嗜碱性粒细胞的细胞质在碱性染色中呈蓝色。

E嗜酸性粒细胞：细胞质嗜酸性粒细胞呈红色。

丰度

嗜碱性粒细胞少于0.5%。

嗜酸性粒细胞：1-5%的白细胞是嗜酸性粒细胞。

功能

嗜碱性粒细胞：嗜碱性粒细胞可以通过释放肝素、组胺和血清素来**炎症反应。

Image Courtesy: “Blausen 0352 Eosinophil” by BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff. “Blausen gallery 2014”. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. – Own work. (CC BY 3.0 ) via Wikimedia Comm*** “Blausen 0077 Basophil” by BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff. “Blausen gallery 2014”. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. – Own work.  (CC BY 3.0) via Wikimedia Comm***